Characterization of a rare blaVIM-4 metallo-β-lactamase-producing Serratia marcescens clinical isolate in Hungary
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چکیده
منابع مشابه
Emergence of metallo-β-lactamase GIM-1 in a clinical isolate of Serratia marcescens.
The metallo-β-lactamase GIM-1 (German imipenemase) has been found so far only in clinical isolates of Pseudomonas aeruginosa from Germany. Here we report the detection of bla(GIM-1) in a clinical strain of Serratia marcescens that was isolated from urine, blood, and wound samples over a period of 20 months. The strain was repeatedly isolated from one patient in two German hospitals and an outpa...
متن کاملIsolation of an integron-borne blaVIM-4 type metallo-beta-lactamase gene from a carbapenem-resistant Pseudomonas aeruginosa clinical isolate in Hungary.
The first integron-borne metallo-beta-lactamase gene was isolated in Hungary. The bla(VIM-4) gene is located on a class 1 integron that also carries a novel bla(OXA)-like gene. The integron is harbored by a serotype O12 Pseudomonas aeruginosa strain and shows high structural similarity to integrons isolated in Greece and Poland.
متن کاملCloning and Characterization of blaVIM, a New Integron-Borne Metallo-b-Lactamase Gene from a Pseudomonas aeruginosa Clinical Isolate
LAURA LAURETTI, MARIA LETIZIA RICCIO, ANNARITA MAZZARIOL, GIUSEPPE CORNAGLIA, GIANFRANCO AMICOSANTE, ROBERTA FONTANA, AND GIAN MARIA ROSSOLINI* Dipartimento di Biologia Molecolare, Sezione di Microbiologia, Università di Siena, 53100-Siena, Istituto di Microbiologia, Università di Verona, 37134-Verona, and Dipartimento di Scienze e Tecnologie Biomediche e Biometria, Università dell’Aquila, 6710...
متن کاملCloning and characterization of blaVIM, a new integron-borne metallo-beta-lactamase gene from a Pseudomonas aeruginosa clinical isolate.
Production of a metallo-beta-lactamase activity was detected in a carbapenem-resistant Pseudomonas aeruginosa clinical isolate (isolate VR-143/97) from an Italian inpatient at the Verona University Hospital (northern Italy). The metallo-beta-lactamase determinant was isolated from a genomic library of VR-143/97, constructed in an Escherichia coli plasmid vector, by screening for clones with red...
متن کاملOrganic solvent tolerant metallo protease of novel isolate Serratia marcescens PPB-26: production and characterization
Proteases are a class of enzymes that catalyze hydrolysis of peptide bonds of proteins. In this study, 221 proteolytic bacterial isolates were obtained by enrichment culture method from soils of various regions of Himachal Pradesh, India. From these a hyper producer of protease was screened and identified by morphological and physiological testing and by 16S rDNA sequence as Serratia marcescens...
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ژورنال
عنوان ژورنال: Heliyon
سال: 2020
ISSN: 2405-8440
DOI: 10.1016/j.heliyon.2020.e04231